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Mouse Interleukin-4/IL-4 Recombinant Protein (RPES1963)

SKU:
RPES1963
Product Type:
Recombinant Protein
Species:
Mouse
Research Area:
Growth Factors & Cytokines
€236
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Description

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Mouse Interleukin-4/IL-4 Recombinant Protein

Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.

Product Name:Mouse Interleukin-4/IL-4 Recombinant Protein (RPES1963)
Product Code:RPES1963
Size:10µg
Species:Mouse
Expressed Host:Human Cells
Synonyms:Interleukin-4, IL-4, IL4, B-cell IgG differentiation factor, B-cell growth factor 1, B-cell stimulatory factor 1, BSF-1, IGG1 induction factor, Lymphocyte stimulatory factor 1
Accession:P07750
Sequence: His21-Ser140
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Mouse Interleukin-4 is produced by our Mammalian expression system and the target gene encoding His21-Ser140 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by SDS-PAGE
Mol Mass:14.6 kDa
AP Mol Mass:17-19 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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