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Mouse IL2 p40/IL2B Recombinant Protein (RPES1528)

SKU:
RPES1528
Product Type:
Recombinant Protein
Species:
Mouse
Research Area:
Growth Factors & Cytokines
€236
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Description

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Mouse IL2 p40/IL2B Recombinant Protein

Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. It has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.

Product Name:Mouse IL2 p40/IL2B Recombinant Protein (RPES1528)
Product Code:RPES1528
Size:10µg
Species:Mouse
Expressed Host:Human Cells
Synonyms:Interleukin-12 subunit beta, IL-12B, Cytotoxic lymphocyte maturation factor 40 kDa subunit, CLMF p40, IL-12 subunit p40, Il12b
Accession:P43432
Sequence:Met23-Ser335
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Mouse Interleukin-12 subunit beta is produced by our Mammalian expression system and the target gene encoding Met23-Ser335 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by SDS-PAGE
Mol Mass:37.1 kDa
AP Mol Mass:42-55 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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