Recombinant Mouse IL-3 Protein (Trx Tag) (RPES8216)
- SKU:
- RPES8216
- Size:
- 20μg
- Tag:
- N-Trx
- Reactivity:
- Mouse
- Expression Host:
- E.coli
- Accession:
- P01586
Description
| Product Name: | Recombinant Mouse IL-3 Protein (Trx Tag) |
| SKU: | RPES8216 |
| Size: | 20μg |
| Tag: | N-Trx |
| Reactivity: | Mouse |
| Expression Host: | E.coli |
| Accession: | P01586 |
| Sequence: | Ala27-Cys166 |
| Calculated Molecular Weight: | 35.3 kDa |
| Observed Molecular Weight: | 35 kDa |
| Synonyms: | Interleukin, Hematopoietic Growth Factor, Interleukin-3, Mast Cell Growth Factor, MCGF, MCSF, MULTI-CSF, Multipotential Colony-Stimulating Factor, P-Cell Stimulating Factor, P-Cell-Stimulating Factor, Csfmu, Il-3, Il3 |
| Endotoxin: | < 10 EU/mg of the protein as determined by the LAL method |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
IL3 (interleukin 3), also known as IL-3, is a potent growth-promoting cytokine that belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as throμgh monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells. IL3/IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation, and apoptosis. IL3/IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
| Bio-activity: | Not validated for activity |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
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