Recombinant Mouse Hepcidin/HAMP Protein (RPCB1998)
- SKU:
- RPCB1998
- Size:
- 100µg
- Tag:
- N-GST
- Reactivity:
- Mouse
- Expression Host:
- E. coli
Description
| Product Name: | Recombinant Mouse Hepcidin/HAMP Protein |
| SKU: | RPCB1998 |
| Size: | 100µg |
| Tag: | N-GST |
| Reactivity: | Mouse |
| Expression Host: | E. coli |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Mouse Hepcidin/HAMP Protein , tested reactivity inE. coliand has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | <1EU/μg |
| Purity: | > 95% as determined by HPLC. |
| Formulation: | Supplied as a 0.22 μm filtered solution in 50 mM Tris-HCl, 150 mM NaCl, 2 mM DTT, pH 7.5. |
| Gene ID: | 84506 |
Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis.
| Storage: | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
| Swiss-Prot: | Q9EQ21 |
 | Recombinant Mouse Hepcidin/HAMP Protein was determined by SDS- PAGE with Coomassie Blue, showing a band at 29kDa. |
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