Fc receptor-like protein 1, also known as FcR-like protein 1, Fc receptor homolog 1, IFGP family protein 1, Immune receptor translocation-associated protein 5 and FCRL1, is a single-pass type I membrane protein which contains three Ig-like C2-type (immunoglobulin-like) domains. It is a cell-surface membrane protein belonging to FCRL family and is preferentially expressed on B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It is detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. FCRL1 is specifically expressed by mature B lineage cells with higher expression in naive versus memory B cells (at protein level). Human Fc receptor-like molecules (FCRL1, FCRL2, FCRL3, FCRL4, FCRL5) have tyrosine-based immunoregulatory potential and are expressed by B-lineage subpopulations. FCRL1 may function as an activating coreceptor in B cells. It may also function in B cells activation and differentiation.
Product Name:
Mouse FCRL1 Recombinant Protein (RPES1260)
Product Code:
RPES1260
Size:
50µg
Species:
Mouse
Expressed Host:
HEK293 Cells
Synonyms:
Fc receptor-like protein 1, FcR-like protein 1, FcRL1, BXMAS1-like protein 1, mBXMH1, Fc receptor homolog 1, FcRH1, moFcRH1, IFGP family protein 1, mIFGP1, CD307a,Bxmas1,Bxmh1,Bxmh1b,Fcrh1,Fcrh1l,Fcrh1s,Ifgp1 Protein
Accession:
Q8R4Y0-2
Sequence:
Met1-Thr204
Fusion tag:
C-His
Endotoxin:
<1.0 EU per µg of the protein as determined by the LAL method.
Protein Construction:
A DNA sequence encoding the mouse FCRL1 (Q8R4Y0-2) (Met1-Thr204) was expressed with a C-terminal polyhistidine tag.
Purity:
> 95 % as determined by SDS-PAGE
Mol Mass:
21.6 kDa
Formulation:
Lyophilized from sterile PBS, pH 7.4
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
