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Mouse DKK3 Recombinant Protein (RPES3459)

SKU:
RPES3459
Product Type:
Recombinant Protein
Species:
Mouse
€656
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Description

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Mouse DKK3 Recombinant Protein

DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its downregulation contribute to an activation of the beta-catenin signaling pathway.

Product Name:Mouse DKK3 Recombinant Protein (RPES3459)
Product Code:RPES3459
Size:50µg
Species:Mouse
Expressed Host:HEK293 Cells
Synonyms:AW061014,C87148
Accession:NP_056629.1
Sequence:Met 1-Ile 349
Fusion tag:C-His
Endotoxin:<1.0 EU per µg of the protein as determined by the LAL method.
Protein Construction:A DNA sequence encoding the extracellular domain (Met 1-Ile 349) of mouse DKK3 (NP_056629.1) precursor was expressed with a C-terminal polyhistidine tag.
Purity:> 97 % as determined by SDS-PAGE
Mol Mass:38 kDa
AP Mol Mass:65 kDa
Formulation:Lyophilized from sterile PBS, pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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