null

Mouse CD32b/FCGR2B Recombinant Protein (RPES0629)

SKU:
RPES0629
Product Type:
Recombinant Protein
Species:
Mouse
€221
Frequently bought together:

Description

system_update_altDatasheet

Mouse CD32b/FCGR2B Recombinant Protein

Low affinity immunoglobulin gamma Fc region receptor II (CD32B) is a single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains. The inhibitory CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis. Co-ligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may also be a target formonoclonal antibody therapy for malignancies.