null

Recombinant Mouse CD27/TNFRSF7 Protein (Fc Tag) (RPES8477)

SKU:
RPES8477
Size:
20μg
Tag:
C-Fc
Reactivity:
Mouse
Expression Host:
Mammalian
Accession:
P41272
€289
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Recombinant Mouse CD27/TNFRSF7 Protein (Fc Tag)
SKU:RPES8477
Size:20μg
Tag:C-Fc
Reactivity:Mouse
Expression Host:Mammalian
Accession:P41272
Sequence:Pro24-Arg182
Calculated Molecular Weight:42.4 kDa
Observed Molecular Weight:60 kDa
Synonyms:Tnfrsf, Tnfrsf7, Cd27, T14, S152, TNFRSF7, CD27 antigen, CD27L receptor, S152, T-cell activation antigen CD27, Tp55, Tumor necrosis factor receptor superfamily member 7
Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method
Purity:> 90% as determined by reducing SDS-PAGE.

CD27 , also known as TNFRSF7 , is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage , and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer , CD27 has been shown to play roles in lymphoid proliferation , differentiation , and apoptosis.It has an important role in the generation of T cell immunity and is an robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule , the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity , and meanwhile , plays a key role in regulating B-cell differentiation , activation and immunoglobulin synthesis.

Bio-activity:Not validated for activity
Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Related Products