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Recombinant Mouse CCL2/MCP-1 Protein (RPCB1140)

SKU:
RPCB1140
Size:
10µg
Tag:
No tag
Reactivity:
Mouse
Expression Host:
Pichia
€139
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Description

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Product Name:Recombinant Mouse CCL2/MCP-1 Protein
SKU:RPCB1140
Size:10µg
Tag:No tag
Reactivity:Mouse
Expression Host:Pichia
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Mouse CCL2/MCP-1 Protein , tested reactivity inPichiaand has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:<0.1EU/μg
Purity:> 95% by SDS-PAGE.
Formulation:Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Gene ID:20296

Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, belongs to a group of CC chemokines located in chromosome 17q11.2. MCP-1 protein interacts with chemokine C-C motif receptor 2 (CCR2) to activate and recruit monocytes, macrophages, CD4+ T cells and immature dendritic cells to the site of infection. The presence of MCP-1 protein in an adequate concentration is important for granuloma formation and M. tuberculosis clearance.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:P10148
Product ImageRecombinant Mouse CCL2/MCP-1 Protein was determined by SDS- PAGE with Coomassie Blue, showing bands at 14-18 kDa.
Product ImageRecombinant Mouse CCL2 inhibit the proliferation of HUVEC(Human Umbilical Vein Endothelial Cells). The EDâ‚…â‚€ for this effect is 0.20-0.80 ng/mL. Recombinant Mouse CCL2 chemoattract THP-1 cells. The EDâ‚…â‚€ for this effect is typically 2.87-11.48 ng/mL.

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