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Mouse APRIL/TNFSF13 Recombinant Protein (RPES2341)

SKU:
RPES2341
Product Type:
Recombinant Protein
Species:
Mouse
Research Area:
Growth Factors & Cytokines
€212
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Description

system_update_altDatasheet

Mouse APRIL/TNFSF13 Recombinant Protein

Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. TNFSF13 is a Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA and plays a role in the regulation of tumor cell growth. It expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. Its expression by CD4+ T cells inhibits the production of Th2 cytokines and allergic inflammation.

Product Name:Mouse APRIL/TNFSF13 Recombinant Protein (RPES2341)
Product Code:RPES2341
Size:10µg
Species:Mouse
Expressed Host:Human Cells
Synonyms:A proliferation-inducing ligand,TNFSF13,TALL-2,TRDL-1,CD256
Accession:Q9D777
Sequence:Ala96-Leu240
Fusion tag:N-Fc
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Mouse TNFSF13 is produced by our Mammalian expression system and the target gene encoding Ala96-Leu240 is expressed with a Fc tag at the Nterminus.
Purity:> 95% as determined by reducing SDS-PAGE.
Mol Mass:42.7 kDa
AP Mol Mass:50-60 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS,pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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