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Human ZWINT Recombinant Protein (RPES3087)

SKU:
RPES3087
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Cycle
€300
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Description

system_update_altDatasheet

Human ZWINT Recombinant Protein

ZW10 Interactor is localized to the kinetochores from late Prophase to Anaphase and has a uniform distribution in the cytoplasm of Interphase cells. ZWINT interacts ZW10, MIS12 and NDC80 subunit of the NDC80 complex specifically during mitosis. ZWINT is a part of the MIS12 complex which is required for kinetochore formation and spindle checkpoint activity. In addition, ZWINT is required to target ZW10 to the kinetochore at prometaphase.