Recombinant Human VCAM-1/CD106 Protein(His Tag) (RPES8262)
- SKU:
- RPES8262
- Size:
- 20μg
- Tag:
- C-His
- Reactivity:
- Human
- Expression Host:
- stable cell line
- Accession:
- P19320
Description
| Product Name: | Recombinant Human VCAM-1/CD106 Protein (His Tag) |
| SKU: | RPES8262 |
| Size: | 20μg |
| Tag: | C-His |
| Reactivity: | Human |
| Expression Host: | stable cell line |
| Accession: | P19320 |
| Sequence: | Met1-Glu698 |
| Calculated Molecular Weight: | 76.6 kDa |
| Observed Molecular Weight: | 90-100 kDa |
| Synonyms: | CD106, CD106 Antigen, INCAM 100, INCAM-100, L1CAM, MGC99561, V-CAM 1, Vascular Cell Adhesion Molecule 1, Vascular cell adhesion protein 1, VCAM 1, VCAM-1, VCAM1, VCAM1 |
| Endotoxin: | < 1.0 EU/mg of the protein as determined by the LAL method |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
Vascular cell adhesion molecule 1 (VCAM1),also known as CD106,is a transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. VCAM1 is expressed by cytokine-activated endothelium,interacts with integrin VLA4 (α4β1) present on the surface of leukocytes,and mediates both adhesion and signal transduction. It is also expressed either constitutively or inducibly in a variety of other cell types,including vascular smooth muscle cells,differentiating skeletal muscle cells,renal and neural epithelial cells,macrophages (Kupffer cells),dendritic cells,and bone marrow stromal cells .
| Bio-activity: | Not validated for activity |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
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