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Human Tryptase B-2/TPSB2 Recombinant Protein (RPES1487)

SKU:
RPES1487
Product Type:
Recombinant Protein
Species:
Human
€357
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Description

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Human Tryptase B-2/TPSB2 Recombinant Protein

Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.