Description
Product Name: | Recombinant Human Try-2 Protein (His Tag) |
SKU: | RPES8369 |
Size: | 20μg |
Tag: | C-His |
Reactivity: | Human |
Expression Host: | Mammalian |
Accession: | P07478 |
Sequence: | Met1-Ser247 |
Calculated Molecular Weight: | 27.1 kDa |
Observed Molecular Weight: | 30 kDa |
Synonyms: | PRSS, TRYP, Tesp, Serine protease, TRY2TRY, EC 3.4., TRY, PRSS2, TRY2, TRY8, TRYP2, trypsin-2, serine, preproprotein, protease, MGC111183, Tesp4, MGC120174, TRY2TRY8, MGC120175, Anionic trypsinogen, 2 (trypsin 2), EC 3.4.21, EC 3.4.21.4, Serine protease 2, protease serine 2 preproprotein, Trypsin 2, Trypsin II, trypsinogen 2, Trypsinogen 20 |
Endotoxin: | < 1.0 EU/mg of the protein as determined by the LAL method |
Purity: | > 90% as determined by reducing SDS-PAGE. |
Trypsin-2, also known as Trypsin II, Anionic trypsinogen, Serine protease 2, PRSS2 and TRY2, is a secreted protein that belongs to the trypsin serine protease family including Trypsin, PRSS1, PRSS2 and PRSS3. It consists of a signal peptide (residues 1-15), a pro region (residues 16-23), and a proteolytically active mature chain (residues 24-247). PRSS2 contains one peptidase S1 domain. It is secreted into the duodenum, hydrolysing peptides into their smaller building blocks, which is necessary for the uptake of protein in the food. It is secreted by the pancreas in the form of inactive zymogen, trypsinogen and cleaved to its active form in the small intestine when the pancreas is stimulated by cholecystokinin throμgh the common activation mechanism.
Bio-activity: | Not validated for activity |
Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |