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Recombinant Human TNFSF9/4-1BB Ligand Protein (RPCB0166)

SKU:
RPCB0166
Size:
10µg
Tag:
C-His
Reactivity:
Human
Expression Host:
E. coli
€129

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Recombinant Human TNFSF9/4-1BB Ligand Protein
SKU:RPCB0166
Size:10µg
Tag:C-His
Reactivity:Human
Expression Host:E. coli
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Human TNFSF9/4-1BB Ligand Protein , tested reactivity inE. coliand has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:< 0.1 EU/μg of the protein by LAL method.
Purity:> 95% by SDS-PAGE.
Formulation:Lyophilized from a 0.22 μm filtered solution of 50mM Tris, 150mM NaCl, pH 8.0.Contact us for customized product form or formulation.
Gene ID:8744

The protein is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:P41273
Product ImageRecombinant Human TNFSF9/4-1BB Ligand Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 20 kDa.
Product ImageImmobilized recombinant human TNFSF9 at 2 μg/mL (100 μL/well) can bind recombinant human TNFRSF9 with a linear range of 40-100ng/mL.

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