Human TNFRSF1B/CD120b Recombinant Protein (RPES4098)
- SKU:
- RPES4098
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cell Death
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Description
system_update_altDatasheet
Human TNFRSF1B/CD120b Recombinant Protein
Tumor necrosis factor receptor superfamily member 1B is a 461 amino acids protein that belongs to the TNFR (tumor necrosis factor receptor) superfamily characterized by cysteine-rich extracellular domains. It contains 4 TNFR-Cys repeats. TNFRII is expressed in fetal brain. TNFRII is strongly expressed at the cartilage-pannus junction; and plays a major role in a subset of families with multiple cases of rheumatoid arthritis (RA). This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis; which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
| Product Name: | Human TNFRSF1B/CD120b Recombinant Protein (RPES4098) |
| Product Code: | RPES4098 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor 2, Tumor necrosis factor receptor type II, p75, p80 TNF-alpha receptor, TBP-2, TBPII, TNFRSF1B, TNFBR, TNFR2, Tumor Necrosis Factor Receptor II |
| Accession: | P20333 |
| Sequence: | Leu23-Asp257 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human TNFRSF1B is produced by our Mammalian expression system and the target gene encoding Leu23-Asp257 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 26.2 kDa |
| AP Mol Mass: | 40 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB;150mM NaCl;pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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