Recombinant Human TNFRSF12A/TWEAKR/CD266 Protein (RPCB0263)
- SKU:
- RPCB0263
- Size:
- 50µg
- Tag:
- C-hFc&His
- Reactivity:
- Human
- Expression Host:
- HEK293 cells
Frequently bought together:
Description
| Product Name: | Recombinant Human TNFRSF12A/TWEAKR/CD266 Protein |
| SKU: | RPCB0263 |
| Size: | 50µg |
| Tag: | C-hFc&His |
| Reactivity: | Human |
| Expression Host: | HEK293 cells |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human TNFRSF12A/TWEAKR/CD266 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | < 0.1 EU/μg of the protein by LAL method. |
| Purity: | > 90% by SDS-PAGE. |
| Formulation: | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation. |
| Gene ID: | 51330 |
Fn14 (tumor necrosis factor receptor superfamily, member 12A), also known as TNFRSF12A, is the receptor for TNFSF12/TWEAK. Human and mouse TNFRSF12A share 82% aa sequence identity. TNFRSF12A transcript was expressed at high levels in heart, placenta, and kidney, at intermediate levels in lung, skeletal muscle, and pancreas, and at low levels in brain and liver. In addition, elevated TNFRSF12A expression was found in human liver cancer cell lines and hepatocellular carcinoma specimens. TNFRSF12A is the weak inducer of apoptosis in some cell types. It promotes angiogenesis and the proliferation of endothelial cells. TNFRSF12A may modulate cellular adhesion to matrix proteins.
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | Q9NP84 |
 | Recombinant Human TNFRSF12A/TWEAKR/CD266 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 35-45 kDa. |
 | The purity of Human TNFRSF12A/FN14/TWEAKR Protein was greater than 90% as determined by SEC-HPLC. |
Related Products
