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Human TIM1/HAVCR1 Recombinant Protein (RPES2099)

SKU:
RPES2099
Product Type:
Recombinant Protein
Species:
Human
$836
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Description

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Human TIM1/HAVCR1 Recombinant Protein

HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â…  integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.

Product Name:Human TIM1/HAVCR1 Recombinant Protein (RPES2099)
Product Code:RPES2099
Size:50µg
Species:Human
Expressed Host:HEK293 Cells
Synonyms:CD365,HACVR,HAVCR,HAVCR-1,KIM-1,KIM1,TIM,TIM-1,TIM1,TIMD-1,TIMD1
Accession:AAC39862.1
Sequence:Met 1-Val 135
Fusion tag:C-His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:A DNA sequence encoding the N-terminal fragment (Met 1-Val 135) of human KIM1 (AAC39862.1) extracellular domain was fused with a polyhistidine tag at the C-terminus.
Purity:> 97 % as determined by reducing SDS-PAGE.
Mol Mass:15.8 kDa
AP Mol Mass:22-26 kDa
Formulation:Lyophilized from sterile PBS, pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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