Human Tie1 Recombinant Protein (RPES1783)
- SKU:
- RPES1783
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cardiovascular
Frequently bought together:
Description
system_update_altDatasheet
Human Tie1 Recombinant Protein
TIE-1 (Tyrosine Kinase with Ig and EGF Homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily. These receptors are expressed on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis. Human TIE-1 cDNA encodes a 1124 amino acid (aa) residue precursor protein with an 18aa signal peptide, a 727 aa extracellular domain and a 354 aa cytoplasmic domain. so far, two ligands have been described for TIE-2 [angiopoietin-1 (Ang1) and angiopoietin-2 (Ang2)], but no ligand was found for TIE-1.
| Product Name: | Human Tie1 Recombinant Protein (RPES1783) |
| Product Code: | RPES1783 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Tyrosine-Protein Kinase Receptor Tie-1, TIE1, TIE |
| Accession: | P35590 |
| Sequence: | Ala22-Gln760 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Tyrosine Kinase with Immunoglobulin and Epidermal Growth Factor Homology Domains 1 is produced by our Mammalian expression system and the target gene encoding Ala22-Gln760 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 81.0 kDa |
| AP Mol Mass: | 87 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM MES, 150mM NaCl, pH 5.5. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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