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Human THOP1 Recombinant Protein (RPES0647)

SKU:
RPES0647
Product Type:
Recombinant Protein
Species:
Human
$428
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Description

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Human THOP1 Recombinant Protein

Thimet oligopeptidase, a homologue of the CD13 antigen, has been identified in human myeloid leukaemia cells and is considered a potential target for antibody-based therapies. THOP1 is a kininase that uses zinc as a cofactor. Cytosolic peptides are broken down by THOP1, making them unavailable to antigen-presenting cells. Infantile spasms and mental retardation X-linked type 3 are two examples of THOP1-related disorders. THOP1/Thimet oligopeptidase is involved in clathrin-derived vesicle budding and Vesicle-mediated transport. Human THOP1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.

Product Name:Human THOP1 Recombinant Protein (RPES0647)
Product Code:RPES0647
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Thimet Oligopeptidase, Endopeptidase 24.15, MP78, THOP1
Accession:P52888
Sequence:Lys2-Cys689
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Thimet Oligopeptidase is produced by our E.coli expression system and the target gene encoding Lys2-Cys689 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:80.0 kDa
AP Mol Mass:85 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM PB, 100mM NaCl, 10% Glycerol, pH 7.0.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

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