Human Spondin 2/SPON2 Recombinant Protein (RPES0162)
- SKU:
- RPES0162
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cell Biology
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Description
system_update_altDatasheet
Human Spondin 2/SPON2 Recombinant Protein
Spondin-2, also referred to as mindin, belongs to the F-spondin family of secreted extracellular matrix proteins. Spondins are characterised by the presence of F-spondin domains 1 and 2 (FS1 and FS2) at the N-terminus and a thrombospondin-type 1 repeat (TSR1) domain at the C-terminus. Spondin-2 functions as a pattern-recognition molecule for bacterial and viral pathogens and as an integrin ligand for inflammatory cell recruitment and T cell priming. In addition to its roles in promoting neuron outgrowth and inhibiting both cancer and angiogenesis, Spondin-2 plays an important role in the initiation of the immune response and is involved in inflammatory processes.
Product Name: | Human Spondin 2/SPON2 Recombinant Protein (RPES0162) |
Product Code: | RPES0162 |
Size: | 10µg |
Species: | Human |
Expressed Host: | Human Cells |
Synonyms: | Spondin-2, Differentially expressed in cancerous and non-cancerous lung cells 1, DIL-1, Mindin, SPON2 |
Accession: | Q9BUD6 |
Sequence: | Gln27-Val331 |
Fusion tag: | C-6His |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Human Spondin2 is produced by our Mammalian expression system and the target gene encoding Gln27-Val331 is expressed with a 6His tag at the C-terminus. |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Mol Mass: | 34.4 kDa |
AP Mol Mass: | 40 kDa |
Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |