Human SIRPB1/CD172b Recombinant Protein (RPES4853)
- SKU:
- RPES4853
- Product Type:
- Recombinant Protein
- Species:
- Human
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Description
system_update_altDatasheet
Human SIRPB1/CD172b Recombinant Protein
Signal-regulatory protein beta-1 (SIRPB1, CD172b) is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK.
| Product Name: | Human SIRPB1/CD172b Recombinant Protein (RPES4853) |
| Product Code: | RPES4853 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Signal-regulatory protein beta-1, SIRP-beta-1, CD172 antigen-like family member B, CD172b, SIRPB1 |
| Accession: | O00241 |
| Sequence: | Glu30-Glu362 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human SIRPB1 is produced by our Mammalian expression system and the target gene encoding Glu30-Glu362 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 37.4 kDa |
| AP Mol Mass: | 45-55 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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