null

Recombinant Human SIRP-alpha/CD172a Protein (RPCB0482)

SKU:
RPCB0482
Size:
10µg
Tag:
C-His
Reactivity:
Human
Expression Host:
HEK293 cells
€119
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Recombinant Human SIRP-alpha/CD172a Protein
SKU:RPCB0482
Size:10µg
Tag:C-His
Reactivity:Human
Expression Host:HEK293 cells
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Human SIRP-alpha/CD172a Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:< 0.1 EU/μg of the protein by LAL method.
Purity:> 97% by SDS-PAGE.
Formulation:Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Gene ID:140885

The protein is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:P78324
Product ImageRecombinant Human SIRP alpha/CD172a Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 45-57 kDa.
Product ImageImmobilized Recombinant Human SIRPA at 5μg/mL (100 μL/well) can bind Recombinant Human CD47 with a linear range of 0.1-0.4 μg/mL.

Related Products