Human SIGLEC9/CD329 Recombinant Protein (RPES4997)
- SKU:
- RPES4997
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cell Biology
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Description
system_update_altDatasheet
Human SIGLEC9/CD329 Recombinant Protein
Sialic acid-binding Ig-like lectin 9(Siglec 9) is expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils); and found in liver; fetal liver; bone marrow; placenta; spleen and in lower levels in skeletal muscle; fetal brain and so on. It is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It also binds to alpha-2;3- or alpha-2;6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
| Product Name: | Human SIGLEC9/CD329 Recombinant Protein (RPES4997) |
| Product Code: | RPES4997 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Sialic acid-binding Ig-like lectin 9,Siglec-9,CDw329,Protein FOAP-9,SIGLEC9 |
| Accession: | Q9Y336 |
| Sequence: | Gln18-Gly348(Lys100Glu;Ala315Glu) |
| Fusion tag: | C-His |
| Activity: | Measured by the ability of the immobilized protein to support the adhesion of human red blood cells. Approximately 93% will adhere after 5-10 mins incubation at 37 °C. |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human SIGLEC9 is produced by our Mammalian expression system and the target gene encoding Gln18-Gly348(Lys100Glu;Ala315Glu) is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 36.9 kDa |
| AP Mol Mass: | 55-90 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS;2mMEDTA;ph7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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