Human Serglycin/SRGN Recombinant Protein (RPES4435)
- SKU:
- RPES4435
- Product Type:
- Recombinant Protein
- Species:
- Human
Frequently bought together:
Description
system_update_altDatasheet
Human Serglycin/SRGN Recombinant Protein
SRGN is known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of various hematopoietic cells has a protease-resistant peptide core, and is vital for neutralizing hydrolytic enzymes. SRGN is associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. It is required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. SRGN also plays a role in localizing neutrophil elastase in azurophil granules of neutrophils.
Product Name: | Human Serglycin/SRGN Recombinant Protein (RPES4435) |
Product Code: | RPES4435 |
Size: | 20µg |
Species: | Human |
Expressed Host: | HEK293 Cells |
Synonyms: | PPG,PRG,PRG1 |
Accession: | CAA34900.1 |
Sequence: | Met 1-Leu158 |
Fusion tag: | C-His |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | A DNA sequence encoding the human SRGN (CAA34900.1) (Met1-Leu158) was expressed with a polyhistidine tag at the C-terminus. |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Mol Mass: | 16.1 kDa |
Formulation: | Lyophilized from sterile PBS, pH7.4 |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |