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Human Semaphorin 4D/SEMA4D Recombinant Protein (RPES4330)

SKU:
RPES4330
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Developmental Biology
€212
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Description

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Human Semaphorin 4D/SEMA4D Recombinant Protein

Semaphorin-4D is also known as A8;BB18; GR3; CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain; 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells; regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/PYK2; which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.

Product Name:Human Semaphorin 4D/SEMA4D Recombinant Protein (RPES4330)
Product Code:RPES4330
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Semaphorin-4D, A8,BB18, GR3, CD100,C9orf164,CD100,coll-4,M-sema-G,SEMAJ
Accession:Q92854
Sequence:Met22-Arg734
Fusion tag:C-Fc
Activity:Immobilized Mouse PLXDC2 -His(Cat: PKSH032037) at 2µg/ml(100 ?l/well) can bind Human SEMA4D-Fc.
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Semaphorin 4D is produced by our Mammalian expression system and the target gene encoding Met22-Arg734 is expressed with a Fc tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:106.4 kDa
AP Mol Mass:130-170 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS; pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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