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Recombinant Human Semaphorin-3G/SEMA3G Protein (RPCB0978)

SKU:
RPCB0978
Size:
10µg
Tag:
C-His
Reactivity:
Human
Expression Host:
HEK293 cells
€199

Description

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Product Name:Recombinant Human Semaphorin-3G/SEMA3G Protein
SKU:RPCB0978
Size:10µg
Tag:C-His
Reactivity:Human
Expression Host:HEK293 cells
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Human Semaphorin-3G/SEMA3G Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:Please contact us for more information.
Purity:> 90% by SDS-PAGE.
Formulation:Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Gene ID:56920

Semaphorin 3G (Sema3G), also known as Semaphorin sem2, is a class 3 member of the semaphorin family initially identified as regulators of neuron-axonal guidance. More than 30 semaphorins have been discovered and are divided into eight classes: classes 1 and 4-7 are membrane-associated, while classes 2, 3, and 8 are in a secreted form. In vitro analysis shows Sema 3G binds to Neuropilin-2, which forms a receptor complex with Plexin-D1. Via this pathways Sema 3G controls lymphatic vascular patterning by the means of cellular collapse. It shows protective effects in ischemic retinopathies by coordinating interactions of beta -catenin and VE-Cadherin in endothelium. Sema 3G has been shown to be involved in adipocyte differentiation. Knockdown of Sema3G inhibited weight gain through PI3K/Akt/GSK3 beta signaling in the adipose tissue and the AMPK/SREBP-1c pathway in the liver. Thus, Sema 3G is an adipokine essential for adipogenesis, lipogenesis, and insulin resistance and is associated with obesity.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:Q9NS98
Product ImageRecombinant Human Semaphorin-3G/SEMA3G Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 100-115kDa.

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