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S100A8&S100A9 Heterodimer Recombinant Protein (RPES3112)

SKU:
RPES3112
Product Type:
Recombinant Protein
Species:
Human
$510
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Description

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S100A8&S100A9 Heterodimer Recombinant Protein

S100A8 is a member of the S100 family, EF-hand superfamily of Ca-binding proteins. It is produced by neutrophils and monocytes, and forms Ca2+-dependent heterodimer/heterotetramer complexes (termed calprotectin) with S100A9. Calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase.