S100A8&S100A9 Heterodimer Recombinant Protein (RPES3112)
- SKU:
- RPES3112
- Product Type:
- Recombinant Protein
- Species:
- Human
Frequently bought together:
Description
system_update_altDatasheet
S100A8&S100A9 Heterodimer Recombinant Protein
S100A8 is a member of the S100 family, EF-hand superfamily of Ca-binding proteins. It is produced by neutrophils and monocytes, and forms Ca2+-dependent heterodimer/heterotetramer complexes (termed calprotectin) with S100A9. Calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase.
| Product Name: | S100A8&S100A9 Heterodimer Recombinant Protein (RPES3112) |
| Product Code: | RPES3112 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | S100A8/S100A9 Heterodimer |
| Accession: | P05109&P06702 |
| Sequence: | Met 1-Glu93(S100A8)&Thr 2-Pro114(S100A9) |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human S100 Calcium Binding Protein S100A8/S100A9 Heterodimer is produced by our E.coli expression system and the target gene encoding Met1-Glu93(S100A8)&Thr2-Pro114(S100A9) is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 11.7&13.2 kDa |
| AP Mol Mass: | 15 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM HEPES,10%Glycerol,150mM NaCl,2.5mM EDTA,pH 7.4. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
