S100-A7 belongs to the S100 family and has two EF-hand calcium-binding motifs. The reduced calcium binding capacity of one EF-hand at the N-terminus distinguishes S100-A7 from other S100 proteins with known structures. The S100b-A7 protein is a key regulator of many cellular processes, including cell cycle progression and differentiation. S100-A7, is overproduced in hyperproliferative skin disorders and has antibacterial and immunomodulatory properties against bacteria. S100-A7 has been linked to bladder cancer and anal fistula in several studies. S100-A7 regulates two separate pathways: transcriptional repression and the innate immune system. Human S100A7/PSOR1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human S100A7/PSOR1 Recombinant Protein (RPES0169)
Product Code:
RPES0169
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Protein S100-A7, Psoriasin, S100 calcium-binding protein A7, S100A7, PSOR1, S100A7C
Accession:
P31151
Sequence:
Met1-Gln101
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human S100A7 is produced by our E.coli expression system and the target gene encoding Met1-Gln101 is expressed.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
11.5 kDa
AP Mol Mass:
14 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
