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Recombinant Human RNF43 Protein (RPCB1864)

SKU:
RPCB1864
Size:
100µg
Tag:
C-hFC
Reactivity:
Human
Expression Host:
HEK293 cells
€569

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Recombinant Human RNF43 Protein
SKU:RPCB1864
Size:100µg
Tag:C-hFC
Reactivity:Human
Expression Host:HEK293 cells
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Human RNF43 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:<1EU/μg
Purity:> 95% as determined by HPLC
Formulation:Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Gene ID:54894

RNF43 (E3 ubiquitin-protein ligase RNF43 or RING-type E3 ubiquitin transferase RNF43) functions as a tumor suppressor, by exerting a predominant negative feedback mechanism in the Wnt/β-catenin signaling pathway. RNF43 inhibits Wnt/beta-catenin signaling by ubiquitinating Frizzled receptor and targeting it to the lysosomal pathway for degradation.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:Q68DV7
Product ImageHuman RNF43 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Product ImageThe purity of Human RNF43 is greater than 95% as determined by SEC-HPLC.

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