Human Ribonuclease 3/RNASE3 Recombinant Protein (RPES3913)
- SKU:
- RPES3913
- Product Type:
- Recombinant Protein
- Species:
- Human
Frequently bought together:
Description
system_update_altDatasheet
Human Ribonuclease 3/RNASE3 Recombinant Protein
Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a wide variety of biological activities. RNASE3 interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). RNASE3 exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. It promotes E. coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
Product Name: | Human Ribonuclease 3/RNASE3 Recombinant Protein (RPES3913) |
Product Code: | RPES3913 |
Size: | 10µg |
Species: | Human |
Expressed Host: | Human Cells |
Synonyms: | Eosinophil Cationic Protein, ECP, Ribonuclease 3, RNase 3, RNASE3, ECP, RNS3 |
Accession: | P12724 |
Sequence: | Arg28-Ile160 |
Fusion tag: | C-6His |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Human Ribonuclease 3 is produced by our Mammalian expression system and the target gene encoding Arg28-Ile160 is expressed with a 6His tag at the C-terminus. |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Mol Mass: | 16.6 kDa |
AP Mol Mass: | 25 kDa |
Formulation: | Supplied as a 0.2 µm filtered solution of 20mM TrisHCl,150mM NaCl,1mMDTT,10%Glycerol,pH7.5. |
Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |