Human PROS1/Protein S Recombinant Protein (RPES0217)
- SKU:
- RPES0217
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cardiovascular
Frequently bought together:
Description
system_update_altDatasheet
Human PROS1/Protein S Recombinant Protein
PROS1, also known as protein S, is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. PROS1 has two isoforms: a free, functionally active form and an inactive form complexed with C4b-binding protein. Besides its anticoagulant function, PROS1 also acts as an agonist for the tyrosine kinase receptors Tyro3, Axl, and Mer. The endothelium expresses Tyro3, Axl, and Mer and produces protein S. The interaction of protein S with endothelial cells and particularly its effects on angiogenesis have not yet been analyzed.
Product Name: | Human PROS1/Protein S Recombinant Protein (RPES0217) |
Product Code: | RPES0217 |
Size: | 100µg |
Species: | Human |
Expressed Host: | HEK293 Cells |
Synonyms: | PROS,Protein S,PS21,PS22,PS23,PS24,PS25,PSA,THPH5,THPH6 |
Accession: | P07225 |
Sequence: | Met 1-Ser676 |
Fusion tag: | C-His |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | A DNA sequence encoding the human PROS1 (P07225) (Met1-Ser676) was expressed with a polyhistidine tag at the C-terminus. |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Mol Mass: | 74.1 kDa |
AP Mol Mass: | 69-89 kDa |
Formulation: | Lyophilized from sterile PBS, pH 7.4 |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |