Human PPP3R1 Recombinant Protein (His Tag) (Active) (RPES3670)
- SKU:
- RPES3670
- Product Type:
- Recombinant Protein
- Species:
- Human
Frequently bought together:
Description
system_update_altDatasheet
Human PPP3R1 Recombinant Protein
PPP3R1 is an active regulatory subunit of calcineurin. Calcineurin is a calcium-dependent, calcium-modulated protein phosphatase. Calcium sensitivity is modified by PPP3R1. Spinocerebellar ataxia is a PPP3R1-related condition. The phospholipase C pathway, CDK-mediated phosphorylation, and Cdc6 removal are all examples of PPP3R1 related pathways. Human PPP3R1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Human PPP3R1 Recombinant Protein (RPES3670) |
| Product Code: | RPES3670 |
| Size: | 20µg |
| Species: | Human |
| Expressed Host: | Baculovirus-Insect Cells |
| Synonyms: | Calcineurin Subunit B Type 1, Protein Phosphatase 2B Regulatory Subunit 1, Protein Phosphatase 3 Regulatory Subunit B Alpha Osoform 1, PPP3R1, CNA2, CNB |
| Accession: | P63098 |
| Sequence: | Gly2-Val170 |
| Fusion tag: | N-His |
| Activity: | Using the Octet RED System; the affinity constant (Kd) of human PPP3R1-His bound to Human PPIA-His was 6 nM. |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the human PPP3R1 (P63098) (Gly2-Val170) was fused with a polyhistide tag at the N-terminus. |
| Purity: | > 87 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 21.4 kDa |
| AP Mol Mass: | 20 kDa |
| Formulation: | Lyophilized from sterile 50mM Tris; 100mM NaCl; pH 8.0; 10% glycerol; 2mM DTT |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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