Phosphoinositide-3-kinase-interacting protein 1(PIK3IP1) is an enzyme that in humans is encoded by the PIK3IP1 gene.It is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepatocellular carcinoma. The gene encoding PIK3IP1 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
Product Name:
Human PIK3IP1 Recombinant Protein (RPES2001)
Product Code:
RPES2001
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Kringle domain-containing protein HGFL, PIK3IP1, HGFL
Accession:
Q96FE7
Sequence:
Ser22-Thr168
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Phosphoinositide-3-kinase-interacting protein 1 is produced by our Mammalian expression system and the target gene encoding Ser22-Thr168 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
16.7 kDa
AP Mol Mass:
11&30-40 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 50mM TrisHCl,10mM reduced Glutathione,PH8.0.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.