Human PGA4/Pepsinogen A Recombinant Protein (RPES1360)
- SKU:
- RPES1360
- Product Type:
- Recombinant Protein
- Species:
- Human
Frequently bought together:
Description
system_update_altDatasheet
Human PGA4/Pepsinogen A Recombinant Protein
PGA4 (Pepsinogen 4; group I); or Pepsinogen A; is a member of the peptidase A1 family. Pepsin is expressed as a pro-form zymogen; pepsinogen; whose primary structure has an additional 44 amino acids. Pepsin is stored as pepsinogen so it will only be released when needed; and does not digest the body's own proteins in the stomach's lining. Five types of zymogens of pepsins; gastric digestive proteinases; are known: pepsinogens A; B; and F; progastricsin; and prochymosin. There are two major groups of pepsinogen; namely pepsinogen A (PGA) and pepsinogen C (PGC) (or progastricsin); and each frequently has isozymogens. The PGA3; PGA4 and PGA5 genes encode identical human pepsinogen A enzymes.
| Product Name: | Human PGA4/Pepsinogen A Recombinant Protein (RPES1360) |
| Product Code: | RPES1360 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | HEK293 Cells |
| Synonyms: | FLJ58952,FLJ77962,PGA3,PGA4,PGA5 |
| Accession: | P00790 |
| Sequence: | Met 1-Ala 388 |
| Fusion tag: | C-Fc |
| Activity: | Measured by its ability to cleave the fluorogenic peptide substrate; Mca-RPKPVE-Nval-WRK(Dnp)-NH2; AnaSpec; Catalog # 27114.The specific activity is > 3000 pmoles/min/µg.(Activation description: The enzyme achieves its activity under acidic pH) |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the human PGA4 (NP_001073276.1) (Met 1-Ala 388) was fused with the Fc region of human IgG1 at the C-terminus. |
| Purity: | > 80 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 67.3 kDa |
| AP Mol Mass: | 65-70 kDa |
| Formulation: | Lyophilized from sterile PBS; pH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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