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Recombinant Human P53 R175H (HLA-A*02:01) Complex Protein (RPCB1696)

SKU:
RPCB1696
Size:
100µg
Tag:
C-His&Avi
Reactivity:
Human
Expression Host:
HEK293 cells
€779
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Description

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Product Name:Recombinant Human P53 R175H (HLA-A*02:01) Complex Protein
SKU:RPCB1696
Size:100µg
Tag:C-His&Avi
Reactivity:Human
Expression Host:HEK293 cells
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Human P53 R175H (HLA-A*02:01) Complex Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:Less than 1EU per μg by the LAL method.
Purity:> 95% as determined by Tris-Bis PAGEï¼›> 95% as determined by HPLC

p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein.p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:A0A140T913(HLA-A*02:01)&P61769(B2M)& HMTEVVRHC
Product ImageHuman P53 R175H (HLA-A*02:01) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Product ImageThe purity of Human P53 R175H (HLA-A*02:01) is greater than 95% as determined by SEC-HPLC.

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