Recombinant human Olfactomedin-4/OLFM4 Protein (RPCB1525)
- SKU:
- RPCB1525
- Size:
- 10µg
- Tag:
- C-6His
- Reactivity:
- human
- Expression Host:
- HEK293 cells
Description
| Product Name: | Recombinant human Olfactomedin-4/OLFM4 Protein |
| SKU: | RPCB1525 |
| Size: | 10µg |
| Tag: | C-6His |
| Reactivity: | human |
| Expression Host: | HEK293 cells |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant human Olfactomedin-4/OLFM4 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | <1EU/μg |
| Formulation: | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
| Gene ID: | 10562 |
Olfactomedin-4 (OLFM4), previously called GC-1 (G-CSF stimulated clone-1) is an secreted glycoprotein that is a member of the Olfactomedin/Noelin family of protein . It is expressed in epithelial cells of the prostate, small intestine, colon, bone marrow, and in several cancers , and is up-regulated in epithelial cells during inflammation . Mature OLFM4 is a 490 amino acid (aa) protein that is secreted mainly in a polymeric form which is held together by disulfide bonds and carbohydrate interactions . Mature human OLFM4 shares 71% aa sequence identity with mature mouse and rat OLFM4. Olfactomedin-4 (OLFM4) interacts with cell surface lectins and cadherins, which helps cell adhesion and cell spreading of NIH3T3 and 293T/17 cells . OLFM4 plays a critical role in regulating progression of prostate cancer and is also novel biomarker for triple-negative breast cancer .
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | Q6UX06 |
 | Recombinant human Olfactomedin-4/OLFM4 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 65-75 kDa. |
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