Human Neuroplastin/NPTN Recombinant Protein (RPES0338)
- SKU:
- RPES0338
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cell Biology
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Description
system_update_altDatasheet
Human Neuroplastin/NPTN Recombinant Protein
Neuroplastin (NPTN) is a 52-57 kDa member of the Ig-superfamily. Neuroplastin likely serves as a cell adhesion molecule, and is widely expressed in multiple tissues. Human Neuroplastin is 282 amino acids that contions two Ig-like domains and a 38 aa cytoplasmic region. Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. Neuroplastin may also regulate neurite outgrowth by activating the FGFR1 signaling pathway. It may play a role in synaptic plasticity.
Product Name: | Human Neuroplastin/NPTN Recombinant Protein (RPES0338) |
Product Code: | RPES0338 |
Size: | 10µg |
Species: | Human |
Expressed Host: | Human Cells |
Synonyms: | Neuroplastin, Stromal Cell-Derived Receptor 1, SDR-1, NPTN, SDFR1, SDR1 |
Accession: | Q9Y639 |
Sequence: | Gln29-His220 |
Fusion tag: | C-6His |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Human Neuroplastin is produced by our Mammalian expression system and the target gene encoding Gln29-His220 is expressed with a 6His tag at the C-terminus. |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Mol Mass: | 22.7 kDa |
AP Mol Mass: | 40 kDa |
Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |