| Background: | NCAM1, also known as CD56, is a neural adhesion protein (NCAM) which belongs to the immunoglobulin superfamily. NCAM is involved in neural development and in plasticity in the adult brain. UCHL1 is a novel interaction partner of both NCAM isoforms that regulates their ubiquitination and intracellular trafficking. NCAM1 is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. NCAM1 has also been shown to be involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. |
| Name: | Recombinant Human NCAM1 Protein (ECD, His Tag) |
| Size: | 50µg |
| Assay Genie SKU: | RPES1151 |
| Synonyms: | CD56; NCAM; CD56 antigen; MSK39; N-CAM; NCAM; neural cell adhesion molecule 1; neural cell adhesion molecule; NCAM |
| Species: | Human |
| Expression host: | HEK293 Cells |
| Sequence: | Met 1-Pro603 |
| Accession: | NP_001070150.1 |
| Mol Mass: | 66.1 kDa |
| Tag: | C-His |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin: | < 1.0 EU per µg as determined by the LAL method. |
| Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20'C for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation: | Lyophilized from sterile PBS, pH 7.4. 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. 2. Please contact us for any concerns or special |
| Reconstitution: | Please refer to the printed manual for detailed information. |
