Human N-Glycosylase/OGG1 Recombinant Protein (RPES0472)
- SKU:
- RPES0472
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Epigenetics & Nuclear Signaling
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Description
system_update_altDatasheet
Human N-Glycosylase/OGG1 Recombinant Protein
8-oxoGuanineDNAGlycosylase/OGG1 removes 8-oxoguanine, a mutagenic base byproduct that occurs when cells are exposed to reactive oxygen. Mitochondrial targeting signal, as well as lyase action to cleave chains, is included in 8-oxoGuanine DNA Glycosylase/OGG1. Nonpapillary asbestosis, renal cell carcinoma are all conditions linked to OGG1. Deurination and cleavage of the damaged pyrimidine are two 8-oxoGuanine DNA Glycosylase/OGG1 pathways. Human N-Glycosylase/OGG1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name: | Human N-Glycosylase/OGG1 Recombinant Protein (RPES0472) |
Product Code: | RPES0472 |
Size: | 10µg |
Species: | Human |
Expressed Host: | E.coli |
Synonyms: | N-Glycosylase/DNA Lyase, 8-Oxoguanine DNA Glycosylase, DNA-(Apurinic or Apyrimidinic Site) Lyase, AP Lyase, OGG1, MMH, MUTM, OGH1 |
Accession: | O15527 |
Sequence: | Met 1-Gly345 |
Fusion tag: | N-GST |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Human N-Glycosylase is produced by our E.coli expression system and the target gene encoding Met1-Gly345 is expressed with a GST tag at the N-terminus. |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Mol Mass: | 65.1 kDa |
AP Mol Mass: | 66 kDa |
Formulation: | Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 1mM EDTA, 50% Glycerol, pH 7.8. |
Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |