Recombinant Human MUC-16/CA125 Protein (RPCB0928)
- SKU:
- RPCB0928
- Size:
- 10µg
- Tag:
- C-His&Avi
- Reactivity:
- Human
- Expression Host:
- HEK293 cells
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Description
| Product Name: | Recombinant Human MUC-16/CA125 Protein |
| SKU: | RPCB0928 |
| Size: | 10µg |
| Tag: | C-His&Avi |
| Reactivity: | Human |
| Expression Host: | HEK293 cells |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human MUC-16/CA125 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | < 0.1 EU/μg of the protein by LAL method. |
| Purity: | > 95% by SDS-PAGE. |
| Formulation: | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
| Gene ID: | 94025 |
The CA125, also known as the MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. The CA 125 molecule is almost certainly a glycoprotein with a predominance of O-linkages. It is heterogeneous with regard to both size and charge, most likely due to continuous deglycosylation of side chains during its life-span in bodily fluids. It exists as a very large complex (perhaps as much as 4 million daltons) under natural conditions.
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | Q8WXI7 |
 | Recombinant Human MUC-16/CA125 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 45-70kDa. |
 | Immobilized Human CA125 at 5 μg/mL (100 μL/well) can bind Human Mesothelin/MSLN with a linear range of 0.3-17 ng/mL. |
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