Human MTHFS Recombinant Protein (RPES1800)
- SKU:
- RPES1800
- Product Type:
- Recombinant Protein
- Species:
- Human
Frequently bought together:
Description
system_update_altDatasheet
Human MTHFS Recombinant Protein
5-formyltetrahydrofolate cyclo-ligase (MTHFS) belongs to the 5-formyltetrahydrofolate cyclo-ligase family. It is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, contributes to tetrahydrofolate metabolism. MTHFS helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion.
| Product Name: | Human MTHFS Recombinant Protein (RPES1800) |
| Product Code: | RPES1800 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | 5-formyltetrahydrofolate cyclo-ligase,5,10-methenyl-tetrahydrofolate synthetase,MTHFS,Methenyl-THF synthetase |
| Accession: | P49914 |
| Sequence: | Met 1-Ala203 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human 5-formyltetrahydrofolate cyclo-ligase is produced by our E.coli expression system and the target gene encoding Met1-Ala203 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 24.3 kDa |
| AP Mol Mass: | 28 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM Tris,200mM Nacl,1mM DTT,50% Glycerol,pH 8.0. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
