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Recombinant Human LMP2 (HLA-A*02:01) Complex Tetramer Protein (RPCB1737)

SKU:
RPCB1737
Size:
100µg
Tag:
C-His&Avi
Reactivity:
Human
Expression Host:
HEK293 cells
$2,603

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Recombinant Human LMP2 (HLA-A*02:01) Complex Tetramer Protein
SKU:RPCB1737
Size:100µg
Tag:C-His&Avi
Reactivity:Human
Expression Host:HEK293 cells
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Human LMP2 (HLA-A*02:01) Complex Tetramer Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:Less than 1EU per μg by the LAL method.
Purity:> 95% as determined by Tris-Bis PAGEï¼›> 95% as determined by HPLC

The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of malignant tumors that highly express LMP2.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:A0A140T913(HLA-A*02:01)&P61769(B2M)&CLGGLLTMV
Product ImageHuman LMP2 (HLA-A*02:01) Tetramer on Tris-Bis PAGE under Non reducing (N) condition. The purity is greater than 95%.
Product ImageThe purity of Human LMP2 (HLA- A*02:01) Tetramer was greater than 95% as determined by SEC-HPLC.

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