Interleukin-16 (IL-16) is a CD8+ T cell-produced cytokine that stimulates chemotaxis in CD4+ T cells and CD4+ monocytes and eosinophils. According to gel filtration analysis, under physiological conditions, human IL-16 is predominantly a multimer that is noncovalently linked, but some IL-16 may be present as a monomer. However, only the multimeric form has chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4+ T cells. IL-16 in both animals and humans shows cross-species reactivity. Human Interleukin6/IL6 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human Interleukin6/IL6 Recombinant Protein (RPES1959)
Recombinant Human Interleukin-16 is produced by our E.coli expression system and the target gene encoding Met1-Ser130 is expressed.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
13.4 kDa
AP Mol Mass:
18 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
