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Human Interleukin-4/IL-4 Recombinant Protein (RPES3551)

SKU:
RPES3551
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immunology
€221
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Description

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Human Interleukin-4/IL-4 Recombinant Protein

Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates a wide range of T and B cell responses, including cell proliferation, survival, and gene expression. IL-4 is made by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells; characterized by their cytokine-secretion profile that includes secretion of IL-4; IL-5; IL-6; IL-10; and IL-13; which favor a humoral immune response. IL-4 has a significant influence on the switching of immunoglobulins to the IgG1 and IgE isotypes. Excessive Th2 cell IL-4 activity has been linked to increased IgE production and an allergic response. Human Interleukin-4/IL-4 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.