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Recombinant Human Interferon omega-1/IFNW1 Protein (RPCB1248)

SKU:
RPCB1248
Size:
10µg
Tag:
C-6His
Reactivity:
Human
Expression Host:
HEK293 cells
€119
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Description

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Product Name:Recombinant Human Interferon omega-1/IFNW1 Protein
SKU:RPCB1248
Size:10µg
Tag:C-6His
Reactivity:Human
Expression Host:HEK293 cells
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Human Interferon omega-1/IFNW1 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:< 0.1EU/μg
Purity:> 97% by SDS-PAGE.
Formulation:Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Gene ID:3467

IFNs are a large family of proteins having antiviral, antiproliferative, and immunomodulatory effects, and are divided into two major classes, type I and type II, based on differences in receptor binding and nucleotide sequence. Type I IFNs consist of IFN α, β, τ, and ω and bind to the type I IFN receptor, whereas IFN-γ is the only type II IFN and is specific for the type II IFN receptor. Human IFN-ω, was identified by three independent groups in 1985 and is structurally related to IFN-α and -β. Both human IFN-ω and IFN-α are produced by virally induced leukocytes and have similar antiviral activities on human cell lines, and a sizeable proportion (at least 1%) of the total antiviral activity of leukocyte IFN is contributed by IFN-ωl. Also, it was reported that IFN-ω could inhibit the growth of human tumors in vivo.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:P05000
Product ImageRecombinant Human Interferon omega-1/IFNW1 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 22 kDa.
Product ImageMeasured in a cell cytotoxicity assay using TF-1 cells. The ED₅₀ for this effect is 0.13-0.54 ng/mL, corresponding to a specific activity of 1.85 × 106~7.69× 106 units/mg.

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