Interferon-gamma (IFN-g) is a type of interferon that is produced by mitogenically or antigenically stimulated lymphocytes. It is structurally distinct from type I interferon and has a more restricted role in the body's immune response. It has been linked to the production of class II histocompatibility antigens in cells that do not normally express them, resulting in autoimmune disease. Interferon gamma is made by T-cells and natural killer cells that have been activated by antigens, mitogens, or alloantigens. CD4 and CD8 surface antigens on lymphocytes are responsible for its synthesis. IL-2, FGF-basic, and EGF stimulate IFN-gamma production. Human Interferon gamma/IFNG Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human Interferon gamma/IFNG Recombinant Protein (RPES1879)
Recombinant Human Interferon gamma is produced by our Mammalian expression system and the target gene encoding Gln24-Gln166 is expressed.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
16.8 kDa
AP Mol Mass:
16&20-25 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.0.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.