Recombinant Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein (RPCB1643)
- SKU:
- RPCB1643
- Size:
- 100µg
- Tag:
- C-His&Avi
- Reactivity:
- Human
- Expression Host:
- HEK293 cells
Frequently bought together:
Description
Product Name: | Recombinant Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein |
SKU: | RPCB1643 |
Size: | 100µg |
Tag: | C-His&Avi |
Reactivity: | Human |
Expression Host: | HEK293 cells |
Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
Endotoxin: | Less than 1EU per μg by the LAL method. |
Purity: | > 95% as determined by Tris-Bis PAGEï¼›> 95% as determined by HPLC |
Gene ID: | 3685&3694 |
ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion . ITGAV&ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 .
Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
Reconstitution: | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
Swiss-Prot: | P06756-1(ITGAV)&P18564-1(ITGB6) |