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Recombinant Human Insulin Receptor/INSR/CD220 Protein (RPCB1498)

SKU:
RPCB1498
Size:
50µg
Tag:
C-His
Reactivity:
Human
Expression Host:
HEK293 cells
€469

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Recombinant Human Insulin Receptor/INSR/CD220 Protein
SKU:RPCB1498
Size:50µg
Tag:C-His
Reactivity:Human
Expression Host:HEK293 cells
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Human Insulin Receptor/INSR/CD220 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:< 1.0 EU/μg of the protein by LAL method.
Purity:> 95 % by SDS-PAGE.
Formulation:Lyophilized from a 0.22 μm filtered solution PBS, pH 7.4.Contact us for customized product form or formulation.
Gene ID:3643

This protein is a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:P06213
Product ImageRecombinant Human Insulin Receptor/INSR/CD220 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at approximately 125-135 kDa & 40-45 kDa.

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